CT, MRI, PET

Found 21 technologies within CT, MRI, PET RSS ATOM

Orientation-Independent Compositional MRI for Ordered Tissue

2019-280 – A hallmark of joint osteoarthritis (OA) is a progressive loss of cartilage that can cause painful joints or even mobility impairments if the loss becomes severe. MRI has the potential to detect early OA and thus will help scientists to develop an interventional strategy to protect or regenerate cartilage. However, conventional compositional MRI suffers from a well-known “magic angle effect... Read More

Fluorinated Cholesterol Compounds for use as PET Imaging Agents

2019-390 – Researchers at the University of Michigan have developed a suite of compounds and chemical syntheses for the production of 18F-radiolabeled cholesterols, which may be used for positron emission tomography (PET). The compounds are analogs of NP-59, an iodine-containing norcholesterol that has been used for SPECT imaging to detect functional endocrine abnormalities associated with adrenal... Read More

Fluorinated Cholesterol Compounds for use as PET Imaging Agents

2019-036 – Researchers at the University of Michigan have developed a suite of compounds and chemical syntheses for the production of 18F-radiolabeled cholesterols, which may be used for positron emission tomography (PET). The compounds are analogs of NP-59, an iodine-containing norcholesterol that has been used for SPECT imaging to detect functional endocrine abnormalities associated with adrenal... Read More

Fluorinated Cholesterol Compounds for use as PET Imaging Agents

7744 – Researchers at the University of Michigan have developed a suite of compounds and chemical syntheses for the production of 18F-radiolabeled cholesterols, which may be used for positron emission tomography (PET). The compounds are analogs of NP-59, an iodine-containing norcholesterol that has been used for SPECT imaging to detect functional endocrine abnormalities associated with adrenal... Read More

Absolute Temperature Measurement Using Magnetic Susceptibility MRI

2018-474 – Magnetic resonance imaging (MRI) is a widely used tool to generate detailed images of diverse body parts including organs, soft tissue, and bone. Quantitative parametric MRI enables comparison of images across multiple sites, greater objectivity, and application of sophisticated analysis techniques such as artificial intelligence and deep learning. Quantitative parametric imaging requires... Read More

Nanostructure Platforms for Quantitative MRI Validation

2018-421 – Magnetic resonance imaging (MRI) is a widely used tool to generate detailed images of diverse body parts including organs, soft tissue, and bone. Quantitative parametric MRI enables comparison of images across multiple sites, greater objectivity, and application of sophisticated analysis techniques such as artificial intelligence and deep learning. A factor currently limiting widespread... Read More

Analytic Morphomics: High Speed Medical Image Automated Analysis Method

4834 – Millions of medical imaging scans, such as computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) are taken each year to aid medical professionals in treating their patients. However, after the images have served their initial purpose, they are rarely referenced again. Recently, the informatics sciences have grown to encompass morphometry, or the... Read More

Applications of novel ErbB2 selective peptides

6579 – The membrane receptor ErbB2 (also known as HER2/neu) is a member of the epidermal growth factor receptor (EGFR) family. ErbB2 is amplified and overexpressed in many epithelial-derived malignancies including breast, ovarian, and lung cancers. Agents capable of selectively targeting ErbB2 can be used for diagnostics, prognostic indications, imaging and therapeutic applications. The... Read More

Distance-Preserving Penalty Function for Imposing Local Rigidity in Deformable Image Registration

6374 – One of the most popular diagnostics for oncology imaging is computed tomography (CT). Worldwide, the CT market accounts for 17.0 per cent of the total diagnostic medical imaging industry. As CT technology improves, physicians are able to use these tools for better approaches to patient treatment. Radiation therapy is a commonly used treatment for many types of cancers, especially in the... Read More

Luminescent Heteromatallic Metallacrown Complexes for Biological Assays and Imaging

6312 – Sensitized lanthanides are becoming increasingly important across multiple scientific industries because of their stability, long luminescence lifetimes, and narrow emission bands. In the growing field of biological assays there has been demonstrated need for luminescent dyes that emit outside of the visible range where traditional fluorescence measurements suffer from high levels of... Read More

Rapid MRI with a spectrally tailored signal recovery pulse

6089 – A rapid incoherent steady state magnetic resonance imaging (MRI) acquisition method has been developed at the University of Michigan. Balanced steady state free precession (bSSFP) acquisition is often used in magnetic resonance imaging (MRI) due to its high signal-to-noise ratio and T2-weighting. However, bSSFP suffers from off-resonance artifacts. The proposed acquisition method offers image... Read More

Copper Catalyzed [18F]Fluorination of (Mesityl)(Aryl) Iodonium Salts

6172 – Molecular imaging techniques allow us to see biological processes as they happen inside the human body. Positron electron tomography (PET) is one such technique. It is currently used for the diagnosis of cancers, and is being increasingly used for the diagnosis of heart conditions. PET can also be used for the diagnosis of neurological disorders such as Alzheimer’s Disease, Parkinson’s... Read More

Software for Analysis of Dynamic Contrast Enhanced and Dynamic Susceptibility Contrast MRI in Functional Image Analysis Tool

5496 – Dynamic contrast enhanced (DCE) and dynamic susceptibility contrast (DSC) MRI Dynamic contrast enhanced (DCE) and dynamic susceptibility contrast (DSC) MRI, which can be acquired within routine clinical MRI sessions with only a few extra minutes, have been shown to be of great clinical value for diagnosis, staging, therapy guidance and assessment of treatment response for many diseases. ... Read More

Effective photothermal therapy using magnetic nanoparticles

5806 – Administered magnetic nanoparticles aggregate in solid tumors and absorb near-infrared radiation to destroy tumor cells. Currently, gold nanostructures are used in photothermal therapy (PTT) as near-infrared-absorbing nanoparticles. However, gold nanoparticles can undergo melting with laser treatment, are too large to effectively accumulate in solid tumors, and require multiple steps for... Read More

Subvolume Identification from DCE MRI for Prediction of Treament Response

5352 – The impact of therapy on cancer as well as normal organs is hard to predict by conventional means, including tumor size, mean value of physiological image parameters in the tumor, or even voxel-by-voxel analysis of physiological images taken before and during treatment. Additional information for tumor response to therapy might be obtained through physiological parameters, which however... Read More

Subvolume Identification for Prediction of Treatment Outcome

5351 – The impact of therapy on cancer as well as normal organs is hard to predict by conventional means, including tumor size, mean value of physiological image parameters in the tumor, or even voxel-by-voxel analysis of physiological images taken before and during treatment. A change in tumor size often occurs too late for prediction of response. A mean value of a physiological image parameter... Read More

Method for Rapid Incoherent Magnetic Resonance Imaging with T2-Weighing

5144 – Magnetic Resonance Imaging (MRI) is a technology that uses magnetic signals to show the different tissues inside the body creating non-invasive images of the inside of the human body. In 2009 there were over 69 million MRI scans performed in the U.S. alone. The imaging procedure is used commonly for diagnosis for every part of the body, from the brain to the knee. With each scan costing... Read More

Error Analysis and Correction of MRI ADC Measurements for Gradient Nonlinearity

5391 – Diffusion MRI is used in a large fraction of clinical MRI exams, where quantitative “Apparent Diffusion Coefficient (ADC)” values are broadly used as biomarkers of therapy response and also reflect other tissue qualities such as cellular density, edema, and necrosis. However, current ADC measurement is in error due to inevitable imaging gradient non-linearity. Known methods that implement... Read More

Gating of Cardiac X-Ray CT Scans from Projections

2878 – One of the challenges associated with cardiac computed tomography (CT) imaging is resulting artifacts caused by the movement of the beating heart. To date, cardiac CT scanners utilize electrocardiogram (ECG) signals to gate the acquisition of scan data. With ECG cardiac gating, direct and consistent correlation between the phases of the ECG periodic signal and the physical position and... Read More

Radiolabeled Neuronal Nuclear Medicine Imaging and Radiotherapeutic Agents

2984 – The autonomic nervous system plays a critical role in the regulation of cardiac function. Abnormalities of cardiac innervation have been implicated in the pathophysiology of many heart diseases, including sudden cardiac death and congestive heart failure. In an effort to provide clinicians with the ability to regionally map cardiac innervation, several radiotracers for imaging cardiac... Read More

Positron Emitting Internal Marker for Identification of Tissues by PET Scanning

1806 – Medical diagnostic imaging techniques such as computed tomography (CT), magnetic resonance imaging (MRI) and ultrasound often rely on targeting aids or landmarking devices, which help identify anatomical locations of visualized areas. One of the most common methods used to date is the radiopharmaceutically-assisted technique. This method depends on cellular uptake of suitable imaging... Read More