Hydro-Seq: High Sample Efficiency Single Cell Whole Transcriptome Analysis Technology
7243 – To adequately diagnose and treat cancer, cancer cells are studied for particular gene expressions. Research has shown that the most important cells to look for are circulating tumor cells (CTCs) as these give rise to cancer. Traditional technologies for studying gene expression look at a population average, which masks diversity that is often seen in cancer patients. It is estimated that CTCs... Read More
Clinical research training program for allied health professionals and other practicing clinicians
6931 – Welcome to PORT (Practice Oriented Research Training). This program was developed to meet the needs of practicing clinicians who want to become competent and active members of the research enterprise. The materials you download will give you an overview of the PORT program, outline the steps needed to implement the program successfully, and provide a list of resources you will need to achieve... Read More
AMON (All-packet MONitor)
7070 – This technology helps to predict, analyze, and respond to network attacks in a rapid manner. Modern internet infrastructure has several weaknesses which can be exploited by malicious groups or individuals. Distributed denial of service (DDoS) attacks, while relatively simple, can compromise government and business servers, costing hundreds of thousands of dollars. There are even services... Read More
Computationally Efficient 3-D Finite-Element-Based Dynamic Thermal Models of Electric Machines
7104 – With the growing popularity of electric and hybrid electric vehicles (HEVs), electric machines are becoming a critical element of the modern powertrain. However, the performance of electric propulsion systems is significantly constrained by the internal temperatures of the electric machine. Hence, in order to determine the torque and power capabilities of an electric machine under real-time... Read More
Methods and Systems to Protect MEMS Sensors from Intentional Acoustic Interference
7092 – Accelerometers and gyroscopes are commonly used sensors which measure varying forms of motion. Accelerometers measure a type of acceleration typically known as “g-force", while gyroscopes measure angular momentum. In order to make these sensors usable in embedded systems, compact designs for these sensors have been developed in the form of MicroElectroMechanical Systems (MEMS). MEMS devices... Read More
Oracle Data Extraction Flow for Epic Clarity Systems
7040 – With the requirement for medical records to become electronic, healthcare providers and researchers are finding that the handling of large amounts of information, even when accomplished computationally, can be difficult. In particular, if data from an EMR database needs to be moved to some another location, this can be a major challenge. The Extraction, Translation, and Loading (ETL) of... Read More
Waveform Annotation Software
7024 – This technology allows the automated annotation and alignment of waveform data and view said data in an Electronic Medical Record (EMR) system. Examples of waveform data include electrocardiogram for heart monitoring and respiratory data for breathing monitoring, but with the increasing use of wearable biosensors the data is becoming ubiquitous. Waveform data can help doctors to make... Read More
Blended Learning Platform 1.0
7017 – The rise of computing devices like laptops and tablets in the classroom is revolutionizing education. Teachers need simple yet flexible learning management systems to take advantage of the opportunities that technology affords the classroom. The Blended Learning Platform allows teachers to get the most of an environment in which students have their own computing device. It simplifies the... Read More
A Computationally Efficient Graph Theoretical Based Numerical Method for Analyzing Conduction Problems on Arbitrary Geometries
7019 – Heat conduction is an active research area for researchers dealing with problems related to a great amount of fields ranging from thermodynamics to reacting flow processes, combustion, unconfined groundwater flow, composite structures, wave propagation, and to microscale/nanoscale heat transport. Existing numerical solution methods applicable to these problems are dependent on geometry of the... Read More
Mobile app for knee replacement perioperative care
7020 – The number of knee replacement surgeries has almost doubled since 2001, with over 700,000 cases performed in 2011, and are now one of the most costly procedures in the US, with an aggregate cost of over $9 billion in 2008. As The Centers for Medicare and Medicaid Services implement payment models that penalize hospitals for poor outcomes, it has become increasingly important to monitor,... Read More
IMassFrag: Metabolite Identification Software
7009 – IMetabolite identification (MetID) of drug candidates is a critical step in drug discovery and development. MetID can aid medicinal chemists in modifying the metabolic soft spots of a drug candidate in the early stage of drug discovery. Metabolic modification of the compounds may change the pharmacological activity and toxicity of a drug molecule. To reduce the risk of costly... Read More
Your Own Planner: An Interactive Search Engine for Smart Traveling
6906 – This technology makes planning a trip easier, more flexible, and cheaper than existing tools. The average American takes four and a half flights for leisure purposes per year, not to mention the number of train tickets sold and road trips taken. Planning for these trips involves finding the cheapest means of travel, but also a number of other factors such as location of accommodations,... Read More
Chromosome Breakability Index
6835 – This technology allows researchers to determine how likely a given portion of the genome is to translocate. Genomic translocations occur when one section of the genome is moved to another section of the genome, sometimes disrupting or removing important genetic information. These translocations can lead to diseases, including cancer. Being able to predict where translocations will occur... Read More
Ontology and Semantic Web-Based Adverse Event Case Reporting and Analysis System
6836 – Adverse event (AE) reporting systems for drugs and vaccines are required by the sponsored by the Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) for post market monitoring. The official post-marketing safety surveillance program, Vaccine Adverse Event Reporting System (VAERS), and FDA Adverse Event Reporting System (FAERS) are programs to collect... Read More
Computer Tool for Collaborative Play for Child with Autism Spectrum Disorder
6830 – This technology provides a computer-based medium for patients with Autism Spectrum Disorder (ASD) to interact and learn important tactile skills, all in a fun environment developed with feedback from patients and physicians. With [increasing rates of ASD] (http://www.cdc.gov/ncbddd/autism/data.html), innovative new treatments are needed to address the issue. ASD patients tend to respond... Read More
ICU Diary
6829 – This technology provides an easy-to-use, web-based diary for patients in long-stay intensive care units (ICU). Over [5 million patients] (http://www.sccm.org/Communications/Pages/CriticalCareStats.aspx) visit an ICU each year, and long-term ICU stays can result in [negative health effects] ( http://www.wsj.com/articles/SB10001424052702303492504579111361055134336). These [can be alleviated]... Read More
Computer game tool for physical therapy
6828 – This technology helps patient’s complete physical therapy in fun and engaging ways in the comfort of their own home. A major problem in physical therapy is patient compliance with repetitive tasks. But it’s been shown that videogames can be used to increase compliance and enhance recovery. This technology harnesses these advantages of videogames to create a fun tool to help recovery of... Read More
Simulation Framework for Multidisciplinary Reduced-Order Modeling and Aerothermoelastic Analysis of Hypersonic Vehicles
6819 – High speed weapons systems, particularly hypersonic vehicles (HSV), operate in a high energy environment characterized by strong fluid, thermal, and structural interactions that must be adequately modeled in order to design the vehicle and its flight control laws. Due to a lack of ground test facilities which can generate the high energy environment of interest, the primary course of... Read More
Corticocardiac Coupling as a Risk Factor for Sudden Death
6687 – Sudden death occurs in more than 400,000 Americans annually and is a significant and under-recognized consequence of stroke. Identification of patients at risk for sudden death after stroke poses a major challenge. Recently, an animal model of stroke uncovered a surge in synchronous brain and heart electrical activity (corticocardiac coupling) hours before sudden death. This finding was... Read More
Procedure Plan and Comfort Measures for needle phobia
7034 – Intravenous insertions, venipuncture and immunizations are common sources of pain in hospitalized children and in children receiving care in clinics. Pain from these procedures result in short-term suffering and also influence future responses to pain and treatments. A child’s comfort is important to parents as they often are present to watch the procedure and find it difficult to console... Read More
Force Sensing Based on Structure-Borne Sound Propagation
6928 – As mobile devices such as smartphones become increasingly indispensable during everyday life, improved user interfacing becomes more critical to enhancing user experiences with their devices. More improved input methods can create new ways of interaction that can provide entertainment or improve quality of life. However, such methods that require new sensors can be cost-prohibitive and breaks... Read More
Display and Algorithm Tools for Big-Data-based Decision Support
6855 – This technology uses existing patient data to help physicians choose the ideal treatment dosage or method for a given patient. Currently, clinical decision making is not always strongly supported by evidence. There is such a huge amount of medical data being published that determining the correct treatment plan for every disease is difficult. Even for a given patient and a given drug... Read More
Analytic Morphomics: High Speed Medical Image Automated Analysis Method
4834 – Millions of medical imaging scans, such as computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) are taken each year to aid medical professionals in treating their patients. However, after the images have served their initial purpose, they are rarely referenced again. Recently, the informatics sciences have grown to encompass morphometry, or the... Read More
National Registry of Exonerations Mobile App
7018 – This technology is a mobile app of the National Registry of Exonerations that provides notifications when a new exoneration has been added. Last year, there were nearly 150 exonerations, and as of March 2016 there were over 1750 exonerations documented within the registry. The mission of the National Registry of Exonerations is to provide comprehensive information on exonerations of... Read More
Large Addressable Memory Solution for GPUs
6375 – Graphical Processing Units (GPUs) offer more processing power and a more energy efficient solutions than traditional CPUs for intense workloads. These factors have contributed to a boom in GPU use in supercomputers and in data centers across the world. Getting the best performance from GPUs often requires rewriting applications to take advantage of the hundreds of cores available on the GPU... Read More
Collaborative Single Kernel Execution Across Heterogeneous Devices
6360 – In heterogeneous computing, a computer system is equipped with multiple types of processors, each designed to optimally execute specific types of tasks. Historically, central processing units (CPUs) handle non data-parallel work such as sequential code and data transfer management, while graphics processing units (GPUs) handle data-parallel work due to their massive number of cores.... Read More
Milk Room Inventory Database
6897 – Experience Infant feeding preparation rooms are becoming an essential service for preparation of human milk in inpatient neonatal and infant care. Infant feeding preparation rooms allow new mothers the opportunity to have their milk properly stored, handled, and prepared as medically needed for their infant. As outlined and recommended by the Academy of Nutrition and Dietetics it is... Read More
Books of Lesson Plans for Preschool Teachers
6905 – This product is a collection of lesson plans for preschool teachers. There are approximately [half a million] (http://www.bls.gov/ooh/education-training-and-library/preschool-teachers.htm) preschool teachers in the US, and the occupation has a high turnover. First-year teachers, in particular, spend a [huge amount of time on developing lesson plans] ... Read More
In-home physical therapy tool for Brachial plexus palsy using Physically Assistive Therapy for Hands (PATH)
6518 – In-home physical therapy represents 90% of all outpatient rehabilitation spending. Despite of high demand and frequent use, in-home physical therapy gets delivered in one of the most outdated and least reliable way; prescription of therapeutic movements as diagrams on a piece of paper relaying 100% on patients' motivation to stick to the exercise regimen. This poses a significant challenge to... Read More
Pre-Surgery Approved Food App
6423 – For many routine surgical operations physicians ask their patients to follow specific diet restrictions for a given amount of time before the procedure. This can often be as simple as “no solid foods”, however some operations require a very specific set of food consumption instructions and failure to follow these guidelines can result in cancelled or rescheduled surgery wasting time and money... Read More
Certainty algorithm for speller brain-computer interface
6917 – This technology improves the accuracy and speed of spelling using EEG signals. Some 7.5 million people in the US have impaired communication. In order for these individuals to communicate, augmented and alternative communication tools are used. These can range from something as simple as a pen to something as complicated as a brain-computer interface. The latter is used in extreme... Read More
Location based diet tracker with just-in-time notifications
6409 – Over 79 million individuals in the US are candidates for a sodium restrictive diet. These diets are commonly prescribed to help patients lower their health risks associated with heart disease and stroke. The proliferation of smartphones in the population allows for patients to have more control and make informed choices while living within the requirements of their diet. This technology... Read More
Logo and Brand Management Application for University Settings - UM Signature Generator
6872 – This technology provides a process for designing a unified logo to project a university’s particular brand. Often, different departments or buildings on a campus will project disparate logos, creating an inconsistent brand. Brand consistency is an important factor in an organization’s success. As universities enter the realm of branding that has so long been important for businesses, new... Read More
The Landscape of Antisense Gene Expression in Human Cancers
6287 – The human genome is widely transcribed, containing protein-coding and non-coding regions. Double-stranded DNA is transcribed to sense transcripts that are eventually translated to form proteins. Some DNA is transcribed into natural antisense RNA (NAT), which are endogenous transcripts that are complementary to sense transcripts. NATs are widespread in eukaryotes with complementary to sense... Read More
An automated high-throughput method for identifying long non-coding RNAs associated with cancer
6286 – Cancer is the second leading cause of death in the United States. While recent efforts at analyzing the transcriptome of cancer patients have focused on studying protein-encoding genes, several long non-coding RNA (lncRNA) transcriptions have been found to promote oncogenesis. Previous attempts at identifying these cancer-associated lncRNAs have been limited. The evolution of high-throughput... Read More
Decision Matrix for Education and Competency Evaluation
6760 – A medical error is a preventable adverse effect of care that occur in 8-12% of all hospitalizations. These errors contribute to 210,000 deaths due to preventable harm and an annual cost of $17.1 billion dollars from excess hospital costs and lost productivity from missed work. Examples of preventable errors include technical errors, diagnosis, failure to prevent injury, and errors in the use... Read More
Algorithm to Identify Patients with Hepatocellular Carcinoma
5396 – Predictive Modeling for Assessing Patient Risk for HCC Researchers in the Department of Statistics and Doctors at the University of Michigan Hospital had developed a machine learning algorithm that predicts the presence of HCC in patients. The predictive model uses results from standard laboratory tests as predictors of HCC. In a clinical trial from 2004 to 2010, the team demonstrated... Read More
Responsible Conduct of Research for K Awardees (RCR4K) Seminar Series
6753 – This training is designed to help meet the responsible conduct of research (RCR) training requirements for NIH K awardees. Every year, the National Institute of Health (NIH), the National Science Foundation (NSF), and other organizations fund hundreds of early career investigators with mentored career development awards (NIH K). The government requires that anyone receiving federal... Read More
Online concussion education for parents and coaches
6751 – Cerebral concussions are notoriously difficult for sports medicine teams to evaluate and manage. These “invisible injuries” are often difficult to diagnose, but have the potential to lead to severe long-term health conditions, such as postconcussion syndrome and chronic traumatic encephalopathy. Determination of when it is safe for an athlete to return-to-play can help prevent further injury.... Read More
WeCareAdvisor
6684 – In the US, there are 15 million caregivers for approximately 10 million individuals with dementia. In dementia, approximately 90% of patients experience non-cognitive neuropsychiatric symptoms (NPS), which are disruptive symptoms such as agitation, aggression, repetitive questioning and wandering. Currently, common practice is to prescribe antipsychotic medications for NPS. This technology... Read More
Software for Identification of Common Protein-Protein Interfaces with Applications to Viral Inhibitors and Vaccines
6496 – Interactions between proteins are ubiquitous in biology and have recently garnered much attention from the drug discovery and protein engineering community. Although evidence suggests about 80% of proteins exists in one or more protein complexes during their lifetimes, relatively little is known about the structural evolution of protein interfaces and how they can be exploited as drug... Read More
Mobile Application To Assess Symptoms of Atrial Fibrillation
6448 – Atrial fibrillation is the most common heart rhythm disturbance in the United States, affecting over 2 million individuals. More than 150,000 new cases are diagnosed each year and, with the incidence of atrial fibrillation increasing with age and a growing ageing population, numbers of patients are expected to increase 150% by 2050. Atrial fibrillation is characterized by disorganized... Read More
Smartphone app for aphasia therapy
6294 – After a stroke, the road to recovery is anything but simple. In nearly 40 percent of cases – as well as in other instances of brain trauma – patients will develop a speech-language disorder called aphasia. This condition currently hinders the ability of over 1 million Americans to understand and be understood in both written and verbal communication. Although intensive therapy has been proven... Read More
Software for Simulating High Temperature Gas Flow
5762 – High Performance Flow Modeling of Spacecraft and Atmospheric Vehicles Re-entry vehicles designed for space exploration are usually equipped with thermal protection systems (TPS) made of ablative material which is one of the key components of their design. Through the use of ablators the energy absorbed by the removal of material from the surface is not used to heat the TPS, thus keeping the... Read More
iCanDecide Conjoint Analysis Breast Cancer Treatment Decision Aid
6440 – iCanDecide is a medical decision aid platform for patients newly diagnosed with breast Cancer. Worldwide over 700 million women are diagnosed with breast cancer each year. Due to the prevalence of breast cancer in society many patients hold preconceptions of treatment options and opinions towards certain treatments, in addition to their personal values. iCanDecide utilized proven marketing... Read More
Evidence-based Learning Method for K-12 Students to Evaluate the Ecological Impacts of Climate Change
6333 – In an increasingly complex world, it is critical that all students gain practical knowledge and firm grasp of science in order to fully comprehend the world and make informed decisions. Multimedia tools continue to play a key role in keeping students more engaged and helping them understand scientific concepts better. Understanding nature is especially critical with issues such as global... Read More
Online evidence-based practice training modules
6096 – Described here is the development of software modules designed to stimulate and support evidence-based practice into behavioral healthcare practices. These web-based training modules were developed based on six basic elements Engagement and Relationship Building Skills, Behavioral Skills, Cognitive Behavioral Skills, Problem Solving Skills, Acceptance Based Skills, Motivational Enhancement... Read More
Teaching and Technology Collaborative Workshop Registration System
6334 – Effectively scheduling and advertising events is critical to ensuring successful outcomes in academic, corporate, and government fields – one report estimated that the software-based scheduling market exceeded $5 billion in 2012. Further, collecting data on registered participants, facilitating social media interaction, and maintaining a wait list of interested parties is fundamental to this... Read More
Mobile Game for Spinal Cord Injury Health and Behavioral Rehabilitation
6349 – Patients of spinal cord injuries (SCI) must learn to manage a lifestyle dramatically different following their impairment. Changes in mobility, disabilities, healthcare scheduling, diet, nutrition, and exercise are just a few examples of the new challenges they have to cope with. This project uses the core principles of evidence-based health mechanics and packages them into a fun and engaging... Read More
An Adaptable Learning Analytics Tool to Identify At-Risk Students
6275 – This solution uses an automated statistical model to identify students at risk of attrition. This will allow students or administrators to take necessary interventions and steps to ensure student retention and success. Student attrition is a major factor affecting university income, representing a loss of nearly [10% of potential revenues.] (http://seatssoftware.com/student-retention.html)... Read More