Office of Technology Transfer – University of Michigan

PON3 and Uses Thereof

Technology #1855d1

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Bert N. LaDu
Managed By
Stefan Koehler
Senior Licensing Specialist, Health Technologies 734-764-4290

The present invention relates to paraoxonase genes, in particular PON3. The present invention provides isolated nucleotide sequence encoding PON3, wild type and mutant PON3 peptides. The present invention also provides methods for using PON3 to screen compounds for the ability to alter PON3 associated activities, methods for generating antibodies useful in the detection of PON3, and methods of treating and preventing oxidative damage, sepsis, chemical toxicity, and other conditions.

US patent 10/184,194