Current micro/nanofluidic technologies have limitations of planar fabrication, lithographic resolution limits, and sub-optimal materials for rapid prototyping.
This technology relates to imprint lithography to pattern a substrate for immobilizing target molecules comprises a substrate having a plurality of binding regions for binding select target molecules, with target-molecule-capturing agent immobilized at the binding regions. The binding regions are interspersed among other non-binding regions. The binding regions are of sub-micron size, have high selectivity and high binding capacity, and prevent or at least minimize loss of target molecule activity.
Applications and Advantages
- Selective surface functionalization for-nl-biosensors and other devices
- The ability to precisely position-nl-proteins opens up new areas of research-nl-as well as enabling the development of-nl-low-cost and robust nanotechnology of-nl-unprecedented small scale and efficiency.