Office of Technology Transfer – University of Michigan

Multifunctional CVD Coatings

Technology #3333

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Categories
Researchers
Joerg Lahann
Managed By
Mutsumi Yoshida
Licensing and Market Specialist 734.763.0441
Patent Protection
US Patent 8,399,047
Publications
Multi-potent polymer coatings based on chemical vapor deposition co-polymerization
Advanced Materials, Volume 18. Page 1521

Background

In various biomedical applications including diagnostics, tissue engineering, and basic study of cell adhesion and motility, there is a growing need for controlled and stable immobilization of one or more (bio)molecules onto a substrate. While several approaches exist to immobilize a single type of molecule to a substrate, techniques to simultaneously present controlled ratios of multiple molecules are not as readily available.

Technology

This invention is based on chemical vapor deposition (CVD) polymerization technique to multiple substituted [2.2]paracyclophanes on a substrate. Using this coating technology, surfaces can present a variety of functional groups including amines, esters, aldehydes, and alcohols, which can subsequently be utilized to covalently bind (bio)molecules. As the ratios of starting monomers is controllable, so too is the ratio of functional groups present on the modified surface. The CVD process is a one-step coating technique, and is performed without any solvents or catalysts, which minimizes surface contamination. Moreover, this technique can be applied to a variety of 3-dimensional structures and the coatings are stable and robust in various environments.

Applications and Advantages

Applications

  • Biomedical diagnostics/assays
  • Micrototal analytical systems
  • Tissue engineering
  • Cell shape/adhesion/motility studies

Advantages

  • Flexibility functionalizing material surface-nl-without altering bulk properties
  • Modular format
  • One-step process without any need for post-treatment