Office of Technology Transfer – University of Michigan

Bio-Artificial Neuro Muscular Interface Device

Technology #4018

Background

Chronic implantation of electrodes and neural prosthetic devices in the central nervous system may be associated with tissue injury and inflammation. The encapsulation of implanted electrodes by glia and immune cells often lead to neuronal loss in the vicinity of the electrode, and prevention of signal transduction. Improved biocompatibility and associated electrical functionality of the electrodes will significantly enhance the function of such neural prosthetic devices and electrodes to maintain long-term communications with neurons.

Technology

University of Michigan researchers have developed an implantable device to interface living neural tissue with electronic devices for extended period (e.g. >10 years). This device, named “Bio-artificial neuro-muscular interface” (BANMI), is comprised of interacting synthetic/natural materials, biological components, and electronic devices. In this invention, conjugated polymers provide a functional electrical interface for charge transfer and signal transduction between the nervous system and an electronic device (e.g. robotic prosthetic limb, retinal implant, microchip).

Applications and Advantages

Applications

  • For other implant applications requiring an interface between the nervous system and an electronic device

Advantages

  • Improved long-term function and biocompatibility