I-TASSER (Iterative Threading ASSEmbly Refinement) is an advanced computer algorithm for protein structure and function predictions. Structural templates are first identified from the PDB by the multiple-threading program LOMETS; full-length models are then constructed by iterative template fragment assembly simulations; function inslights of the target are finally derived by comparing the 3D models with the protein function database BioLiP. I-TASSER (as ‘Zhang-Server’) was ranked as the No 1 server for protein structure prediction in recent CASP7, CASP8, CASP9, CASP10, and CASP11 experiments. It was also ranked as the best for function prediction in CASP9. The academic use server is in active development with the goal to provide the most accurate structural and function predictions using state-of-the-art algorithms.
I-TASSER Academic Licensing
Academic users interested in licensing the I-TASSER server please follow the licensing links to the right
I-TASSER Commercial Licensing
Commercial users interested in licensing the I-TASSER product should contact our commercial partner DNAStar regarding their NovaFold product at http://www.dnastar.com/t-products-NovaFold.aspx