Office of Technology Transfer – University of Michigan

I-TASSER Protein Structure Prediction Software

Technology #4949

Questions about this technology? Ask a Technology Manager

Download Printable PDF

License this Technology
I-TASSER - Academic Site License
Yang Zhang
Managed By
Drew Bennett
Associate Director - Software Licensing 734-615-4004

I-TASSER (Iterative Threading ASSEmbly Refinement) is an advanced computer algorithm for protein structure and function predictions. Structural templates are first identified from the PDB by the multiple-threading program LOMETS; full-length models are then constructed by iterative template fragment assembly simulations; function inslights of the target are finally derived by comparing the 3D models with the protein function database BioLiP. I-TASSER (as ‘Zhang-Server’) was ranked as the No 1 server for protein structure prediction in recent CASP7, CASP8, CASP9, CASP10, and CASP11 experiments. It was also ranked as the best for function prediction in CASP9. The academic use server is in active development with the goal to provide the most accurate structural and function predictions using state-of-the-art algorithms.

I-TASSER Academic Licensing

Academic users interested in licensing the I-TASSER server please follow the licensing links to the right

I-TASSER Commercial Licensing

Commercial users interested in licensing the I-TASSER product should contact our commercial partner DNAStar regarding their NovaFold product at