Office of Technology Transfer – University of Michigan

Non-invasive Blood Pressure Monitor for Permissive Hypotension in Critical Care

Technology #5907

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Continuous Non-Invasicce Blood Pressure Monitor to Maintain Permissive Hypotension
Kevin Ward
Managed By
Bryce Pilz
Director Licensing 734-615-8433
Patent Protection
US Patent Pending

Permissive hypotension in pre-hospital and critical care environments helps prevent re-bleeding from severe injuries. Continuous non-invasive blood pressure monitoring is essential in maintaining permissive hypotension, but is challenging in the pre-hospital setting. However, invasive methods pose risks such as infections. Researchers at the University of Michigan have developed a technology that would monitor blood pressure and advise clinicians on the appropriate measures to maintain permissive hypotension. This device could significantly improve the emergency treatment of traumatic injury with severe bleeding and could thus help reduce trauma related deaths. Bleeding (hemorrhage) causes 30-50% of the trauma associated deaths. This technology could impact a significant patient population since traumatic injury results in 42 million hospital visits a year and about 2 million hospital admissions a year.

Continuous Blood Pressure Information to Maintain Permissive Hypotension

The reliability of traditional non-invasive blood pressure monitors is unverified in critical care environments. Thus, maintaining permissive hypotension can be challenging. This device combines a non-invasive blood perfusion measurement and a cuff based pressure measurement to determine systolic blood pressure. The device alerts clinicians to changes in blood pressure and also advises the clinician on appropriate perfusion options. This device would thus help clinicians maintain permissive hypotension more effectively and help reduce deaths from severe trauma.


  • Monitor systolic blood pressure in critical care environments
  • Monitor systolic blood pressure in operations and other hospital settings


  • Non-invasive
  • Reliable
  • Alerts clinicians and advises on perfusion options